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Understanding Sepsis: A Case Study Analysis

Scenario: Marie is a 27 year old female who is homeless. She arrives at the emergency department with complaints pain in her left foot. After an assessment you discover that she has an open wound on the bottom of her left foot that is red, swollen, and draining green fluid. Cellulitis is present up the leg to the knee. She states she has no chronic medical illnesses and doesn’t take any medication. She is alert and oriented to person, place and time. Her vitals are BP: 100/78 (her normal is 120/80), Heart Rate 100, Temperature 100.5, Pulse Ox 98%, respiratory rate is 22.
1. What condition are you suspecting?
2. Does she have at least 2 criteria for Systemic Inflammatory Response
Syndrome? If so, list the criteria.
3. What are your next steps?
4. What medication do you expect to be given, if any?
5. What labs do you expect the doctor to order?
Abnormal lab results come back as:
Lactate: 4.2
WBC: 15,000
HCT: 42
After fluids were given the vitals were rechecked: BP 88/67, HR114, RR 28,
and Temperature 101.5. She states she feels chills. Patient appears pale.
6. Is she improving?
7. What do you expect the licensed practitioner to order?
The patient arrives to the intensive care unit and is monitored. Fluids and the
IV antibiotics continue. Approximately 4 hours after the initial lactate results
were completed, they drew another lactate blood sample. The results were
now 2.4. The patient remains in the ICU for 2days until she is transferred to
the medical surgical floor for monitoring.
8. If she was not improving, what would she be at risk for?
ADDITIONAL QUESTIONS (response to all is required):
9. What makes a person high risk for infection?
10. Define sepsis
11. In your own words, explain septic shock?
12. In your own words, explain the pathophysiology of Septic shock:
13. Give 2 examples of medications that can be used to treat Sepsis:

Sample Answer

 

Understanding Sepsis: A Case Study Analysis

1. Suspected Condition: The symptoms described in the scenario, including an open wound with redness, swelling, and green fluid drainage, along with cellulitis extending up the leg, indicate a potential diagnosis of sepsis.

2. Criteria for Systemic Inflammatory Response Syndrome (SIRS): Yes, the patient meets at least 2 criteria for SIRS. The criteria include an elevated heart rate (HR 100) and an abnormal temperature (100.5°F).

3. Next Steps: Given the patient’s deteriorating condition, immediate interventions are crucial. The next steps would involve initiating treatment for sepsis, ensuring adequate fluid resuscitation, administering antibiotics, and closely monitoring vital signs.

4. Expected Medication: The patient is likely to be given broad-spectrum antibiotics to target the suspected infection causing the sepsis.

5. Expected Lab Orders: The doctor may order additional labs to further assess the patient’s condition, such as blood cultures, a complete metabolic panel, and coagulation studies.

6. Improvement: The patient’s worsening vital signs, along with the presence of chills and pale appearance, suggest a progression of the infection. The decrease in lactate levels after fluid administration is a positive sign but does not necessarily indicate overall improvement.

7. Expected Orders: The licensed practitioner may order continued fluid resuscitation, close monitoring of vitals, adjustments in antibiotic therapy based on culture results if available, and consultation with specialists as needed.

8. Risk Factors if Not Improving: If the patient was not improving, she would be at risk for complications such as septic shock, multiple organ dysfunction syndrome (MODS), or even death.

Additional Questions:

9. High Risk for Infection: Factors that can make a person high risk for infection include immunocompromised status (e.g., HIV/AIDS, chemotherapy), advanced age, diabetes, chronic diseases, invasive medical procedures, and poor wound care.

10. Definition of Sepsis: Sepsis is a life-threatening condition that occurs when the body’s response to an infection leads to widespread inflammation, causing organ dysfunction and potential failure.

11. Septic Shock Explanation: Septic shock is a severe form of sepsis characterized by profound circulatory, cellular, and metabolic abnormalities that lead to a state of acute circulatory failure.

12. Pathophysiology of Septic Shock: Septic shock involves a complex cascade of events triggered by an infection, resulting in systemic inflammation, vasodilation, increased capillary permeability, microvascular dysfunction, tissue hypoperfusion, and ultimately organ damage.

13. Medications for Sepsis: Two examples of medications used to treat sepsis include antibiotics (to target the underlying infection) and vasopressors (to support blood pressure in cases of septic shock). Additionally, corticosteroids may be used in some cases to modulate the inflammatory response.

 

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