Write a Cancer Review paper covering the recommended topic related to current cancer research.
Cancer Review Recommended Topic:
Mechanisms of EGFR-targeted therapy resistance
Chong CR, Jänne PA. The quest to overcome resistance to EGFR-targeted therapies in cancer. Nat Med. 2013 Nov;19(11):1389-400. doi: 10.1038/nm.3388
Here are the specific guidelines:
Write a literature review on the topic of interest
o Identify, interpret, summarize and synthesize the relevant literature
Identify possible gaps in the knowledge
Formulate a clear and focused research question that should fill gaps in existing knowledge
– Research question should not be too broad
– Research question should start with Why? How? What? How much? How long? How often?
– Research question should shape the problem into a testable hypothesis
– Research question should lead to an appropriate study design and methodology
– Many of the clinical and research questions can be formulated using the PICO principle:
https://guides.mclibrary.duke.edu/ebm/pico