Category: Chemistry

Williamson ether synthesis

Posted on | by

 

Explain an organic reaction to the general public to make it understandable even if it is a complicated topic.
Which functional group are you targeting with your chosen reaction?
Which functional group are you obtaining?
Why is this reaction used in drug discovery?
What is the mechanism (you should draw the mechanism with arrows and electrons) for your reaction?
Please CLEARLY draw the molecule and mechanism on paper.
What are the reagents used in the reaction such as solvents? What are the conditions of the reaction? Are there any side products formed during the reactions? If yes, how can you limit them?

 

Swern oxidation

Posted on | by

 

Explain an organic reaction to the general public to make it understandable even if it is a complicated topic.
Which functional group are you targeting with your chosen reaction?
Which functional group are you obtaining?
Why is this reaction used in drug discovery?
What is the mechanism (you should draw the mechanism with arrows and electrons) for your reaction?
Please CLEARLY draw the molecule and mechanism on paper.
What are the reagents used in the reaction such as solvents? What are the conditions of the reaction? Are there any side products formed during the reactions? If yes, how can you limit them?

Grignard reaction

Posted on | by

 

 

Explain an organic reaction to the general public to make it understandable even if it is a complicated topic.
Which functional group are you targeting with your chosen reaction?
Which functional group are you obtaining?
Why is this reaction used in drug discovery?
What is the mechanism (you should draw the mechanism with arrows and electrons) for your reaction?
Please CLEARLY draw the molecule and mechanism on paper.
What are the reagents used in the reaction such as solvents? What are the conditions of the reaction? Are there any side products formed during the reactions? If yes, how can you limit them?

Claisen condensation

Posted on | by

Explain an organic reaction to the general public to make it understandable even if it is a complicated topic.
Which functional group are you targeting with your chosen reaction?
Which functional group are you obtaining?
Why is this reaction used in drug discovery?
What is the mechanism (you should draw the mechanism with arrows and electrons) for your reaction?
Please CLEARLY draw the molecule and mechanism on paper.
What are the reagents used in the reaction such as solvents? What are the conditions of the reaction? Are there any side products formed during the reactions? If yes, how can you limit them?

Baeyer-Villiger Oxidation

Posted on | by

 

 

Explain an organic reaction to the general public to make it understandable even if it is a complicated topic.
Which functional group are you targeting with your chosen reaction?
Which functional group are you obtaining?
Why is this reaction used in drug discovery?
What is the mechanism (you should draw the mechanism with arrows and electrons) for your reaction?
Please CLEARLY draw the molecule and mechanism on paper.
What are the reagents used in the reaction such as solvents? What are the conditions of the reaction? Are there any side products formed during the reactions? If yes, how can you limit them?

 

 

Friedel-Crafts reaction

Posted on | by

 

Explain an organic reaction to the general public to make it understandable even if it is a complicated topic.
Which functional group are you targeting with your chosen reaction?
Which functional group are you obtaining?
Why is this reaction used in drug discovery?
What is the mechanism (you should draw the mechanism with arrows and electrons) for your reaction?
Please CLEARLY draw the molecule and mechanism on paper.
What are the reagents used in the reaction such as solvents? What are the conditions of the reaction? Are there any side products formed during the reactions? If yes, how can you limit them?

 

 

Elimination reaction (E1 and E2)

Posted on | by

 

Explain an organic reaction to the general public to make it understandable even if it is a complicated topic.
Which functional group are you targeting with your chosen reaction?
Which functional group are you obtaining?
Why is this reaction used in drug discovery?
What is the mechanism (you should draw the mechanism with arrows and electrons) for your reaction?
Please CLEARLY draw the molecule and mechanism on paper.
What are the reagents used in the reaction such as solvents? What are the conditions of the reaction? Are there any side products formed during the reactions? If yes, how can you limit them?

 

 

 

Substitution reaction (SN1 and SN2)

Posted on | by

 

Explain an organic reaction to the general public to make it understandable even if it is a complicated topic.
Which functional group are you targeting with your chosen reaction?
Which functional group are you obtaining?
Why is this reaction used in drug discovery?
What is the mechanism (you should draw the mechanism with arrows and electrons) for your reaction?
Please CLEARLY draw the molecule and mechanism on paper.
What are the reagents used in the reaction such as solvents? What are the conditions of the reaction? Are there any side products formed during the reactions? If yes, how can you limit them?

Sustainable Syntheses

Posted on | by

 

Choose four of the 12 Principles of Green Chemistry **link attached below** one of which must be the “Atom Economy” principle, and evaluate your Dopamine and a potential process for synthesizing Dopamine using your four chosen principles.
Summarize your findings and analysis for your peers, making sure to respond to these prompts:
How does your potential synthesis pathway incorporate your chosen Green Chemistry principles?
Do pharmaceutical companies consider atom efficiency in the synthesis of new drugs? How are companies trying to improve their atom efficiency? Does anything get reused in the process?
What is the difference between percent yield and atom efficiency? Give an example.
https://www.acs.org/greenchemistry/principles/12-principles-of-green-chemistry.html